bloodstream

noun

blood·​stream ˈbləd-ˌstrēm 

1

: the flowing blood in a circulatory system

2

: a mainstream of power or vitality

… introduce into the economic bloodstream a large amount of money …

—Harper's

Examples of bloodstream in a Sentence

The drug is now entering the bloodstream.

Recent Examples on the Web

Sitting in a talk at a local conference, Carleton learned about circulating tumor DNA (ctDNA), which cancer cells release into the bloodstream and can be measured to survey tumor growth. — Allessandra Dicorato, STAT, 8 Oct. 2026

The attorneys believe issues with the IV meant the drug flowed into her body instead of her bloodstream. — Karina Tsui, CNN Money, 8 Oct. 2026

Fiber helps slow the absorption of sugar into the bloodstream, while the fat and protein in peanut butter further slow digestion. — Sarah Jividen, Verywell Health, 8 Oct. 2026

Cold Spring Wellness targets practitioners and biohacking consumers with oral-mucosa strips the company says deliver peptides directly into the bloodstream and bypass the digestive system. — Samantha Agate, Sacbee.com, 7 Oct. 2026

Word History

First Known Use

13th century, in the meaning defined at sense 1

Rhymes for bloodstream

• abeam
• airstream
• daydream
• downstream
• esteem
• extreme
• grapheme
• hakim
• hornbeam
• lexeme
• mainstream
• midstream

Kids Definition

bloodstream

noun

blood·​stream -ˌstrēm 

: the flowing blood in a living thing with a circulatory system

Medical Definition

bloodstream

noun

blood·​stream -ˌstrēm 

: the flowing blood in a circulatory system