creatine

noun

cre·​a·​tine ˈkrē-ə-ˌtēn 

-tᵊn

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in the muscles of vertebrates either free or as phosphocreatine

also : a synthetic usually hydrated form of creatine taken especially as a dietary supplement

Examples of creatine in a Sentence

Recent Examples on the Web

Adding creatine to an exercise and diet intervention resulted in greater reductions in body fat percentage, better preservation of lean body mass, and marked improvements in upper- and lower-body strength compared to a placebo. — Khloe Quill, FOXNews.com, 2 Oct. 2026

Thursdays and Fridays are after-work nights, and members can have a matcha, complete with collagen or creatine shots — or a beer or glass of wine. — Rhonda Richford, Footwear News, 28 Sep. 2026

One of the pledges shredded the cocaine while Robinson added creatine to the cocaine. — Peter Charalambous, ABC News, 23 Sep. 2026

In addition to being high in creatine, herring is packed with other important nutrients, including protein, vitamin D, iodine, selenium, and vitamin B12. — Jillian Kubala, HEALTH, 15 Sep. 2026

Word History

Etymology

French créatine, from Greek kreat-, kreas flesh — more at raw

First Known Use

1840, in the meaning defined above

Phrases Containing creatine

• creatine kinase
• creatine phosphate

Rhymes for creatine

• aten
• clayton
• satan
• statin
• straighten

Medical Definition

creatine

noun

cre·​atine ˈkrē-ə-ˌtēn, -ət-ᵊn 

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in vertebrate muscle either free or as phosphocreatine