: the organized complex of inorganic and organic substances external to the nuclear membrane of a cell and including the cytosol and membrane-bound organelles (such as mitochondria or chloroplasts) see cell illustration

Examples of cytoplasm in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
In the early 1900’s, mosquito researchers discovered that the bacteria itself affects the cytoplasm of host cells, changing their reproductive capabilities. — New Atlas, 1 Oct. 2026 In nonmuscle cells myosin is found in the cytoplasm, often associated with actin networks beneath the cell membrane or within the cell interior. — Encyclopedia Britannica, 3 Apr. 2026 The result is a biochemical system in which the crowdedness of the cytoplasm reflects a cell’s growth and health, Holt said. — Quanta Magazine, 18 Feb. 2026 Surrounding that and protected by an outer shell is the cytoplasm, a frothy liquid of protein-synthesizing ribosomes, energy-producing mitochondria, energy-storing lipids, and the like. — Literary Hub, 28 Oct. 2025 See All Example Sentences for cytoplasm

Word History

Etymology

International Scientific Vocabulary

First Known Use

1857, in the meaning defined above

Time Traveler
The first known use of cytoplasm was in 1857

Cite this Entry

“Cytoplasm.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/cytoplasm. Accessed 9 Oct. 2026.

Kids Definition

: the part of a cell outside the nucleus that includes a fluidlike substance and organelles (as chloroplasts and mitochondria)

Medical Definition

: the organized complex of inorganic and organic substances external to the nuclear membrane of a cell and including the cytosol and membrane-bound organelles (as mitochondria or chloroplasts)

More from Merriam-Webster on cytoplasm

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!