encephalitis

noun

en·​ceph·​a·​li·​tis in-ˌse-fə-ˈlī-təs 

plural encephalitides in-ˌse-fə-ˈli-tə-ˌdēz 

: inflammation of the brain that is caused especially by infection with a virus (such as herpes simplex or West Nile virus) or less commonly by bacterial or fungal infection or autoimmune reaction

Note: Encephalitis may be asymptomatic or present with mild to severe symptoms (such as fever, headache, confusion, seizures, or loss of consciousness) sometimes progressing to coma or death.

encephalitic

in-ˌse-fə-ˈli-tik 

adjective

Examples of encephalitis in a Sentence

Recent Examples on the Web

Other children are developing severe and irreversible neurological damage because of brain inflammation, or encephalitis, Shirey said. — Erika Edwards, NBC news, 5 Oct. 2026

According to Encephalitis International, encephalitis is an inflammation of the brain caused either by an infection or, as in Alice’s case, by the immune system mistakenly attacking the brain. — Adam England, PEOPLE, 26 Sep. 2026

Before vaccination was widely available, about 1,000 people developed chronic disability from acute encephalitis caused by measles annually, according to the CDC. — Jen Christensen, CNN Money, 16 Sep. 2026

Measles can be especially dangerous for young children and pregnant women and can lead to severe complications, such as pneumonia, encephalitis and death. — Katie Wiseman, Louisville Courier Journal, 11 Sep. 2026

Word History

First Known Use

1843, in the meaning defined above

Phrases Containing encephalitis

• Eastern equine encephalitis
• equine encephalitis
• Powassan encephalitis
• Saint Louis encephalitis
• St. Louis encephalitis
• Venezuelan equine encephalitis
• Western equine encephalitis
• West Nile encephalitis

Rhymes for encephalitis

• alveolitis
• bronchiolitis
• caenorhabditis
• cholecystitis
• endometritis
• endophthalmitis
• folliculitis
• periostitis
• peritonitis
• polyneuritis
• thrombophlebitis
• adenitis

Kids Definition

encephalitis

noun

en·​ceph·​a·​li·​tis in-ˌsef-ə-ˈlīt-əs 

(ˌ)en-

: inflammation of the brain

also : a disease marked by encephalitis

Medical Definition

encephalitis

noun

en·​ceph·​a·​li·​tis in-ˌsef-ə-ˈlīt-əs 

plural encephalitides -ˈlit-ə-ˌdēz 

: inflammation of the brain that is caused especially by infection with a virus (such as herpes simplex, varicella zoster, or West Nile virus) or less commonly by bacterial or fungal infection or autoimmune reaction

Note: Encephalitis may be asymptomatic or present with mild to severe symptoms (such as fever, headache, confusion, seizures, or loss of consciousness) sometimes progressing to coma or death.

encephalitic

-ˈlit-ik 

adjective