1
a
: having such speed and kinetic energy as to exhibit relativistic departure from classical laws of motion
—used especially of elementary particles whose velocity has been imparted by an accelerator
b
: of or relating to high-energy particles
2
: yielding a relatively large amount of energy when undergoing hydrolysis

Examples of high-energy in a Sentence

Recent Examples on the Web
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The New York bassist, singer and songwriter has built a reputation for high-energy live performances, both as a solo artist and through her work with other musicians. — Steve Spaleta, Space.com, 3 Oct. 2026 Work released in September, however, showed no accompanying high-energy neutrinos in IceCube’s data at the same time as KM3NeT, and the Antarctic facility has picked up no neutrinos of comparable energy in its 15 years of operations. — Jonathan O'Callaghan, Scientific American, 2 Oct. 2026 That standard reaction produces high-energy neutrons, which wear down reactor walls over time. — Aman Tripathi, Interesting Engineering, 2 Oct. 2026 Michael is there, fast-talking and high-energy, as is one of the show’s head writers, Jenny Bicks. — Kyle MacLachlan, Vanity Fair, 29 Sep. 2026 See All Example Sentences for high-energy

Word History

First Known Use

1934, in the meaning defined at sense 1a

Time Traveler
The first known use of high-energy was in 1934

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Cite this Entry

“High-energy.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/high-energy. Accessed 9 Oct. 2026.

Medical Definition

high-energy

adjective
: yielding a relatively large amount of energy when undergoing hydrolysis
high-energy phosphate bonds in ATP
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