1
: exhibiting excessive tone or tension
a hypertonic baby
a hypertonic bladder
2
: having a higher osmotic pressure than a surrounding medium or a fluid under comparison

Examples of hypertonic in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Use Hypertonic Saline Drops as Needed Even when prepared correctly, hypertonic nasal drops or sprays can irritate the nose and throat. — Stephanie Brown, Verywell Health, 16 Jan. 2025 For example, people who overproduce mucus in response to dirty air may be helped by inhaling hypertonic saline solution. — Linda Carroll, TIME, 30 May 2024 Also referred to as a hypertonic or hyperactive pelvic floor, this describes a state where the muscles in your pelvis hold too much tension and are unable to relax. — Sarah Graham, refinery29.com, 21 May 2021 Sinus rinses like neti pots can help wash out mucus, especially when people use hypertonic saline, Dass said. — Slone Terranella, Detroit Free Press, 19 Apr. 2021 The good news is that hypertonic saline injections seem to work. — Alex Hutchinson, Outside Online, 21 July 2020

Word History

Etymology

International Scientific Vocabulary

First Known Use

1855, in the meaning defined at sense 1

Time Traveler
The first known use of hypertonic was in 1855

Browse Nearby Words

Cite this Entry

“Hypertonic.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/hypertonic. Accessed 9 Oct. 2026.

Medical Definition

hypertonic

adjective
1
: exhibiting excessive tone or tension
a hypertonic baby
a hypertonic bladder
2
: having a higher osmotic pressure than a surrounding medium or a fluid under comparison
animals that produce urine which is hypertonic to their blood
compare hypotonic sense 2, isotonic sense 1
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